Triggered release in lipid bilayer-capped mesoporous silica nanoparticles containing SPION using an alternating magnetic field.

نویسندگان

  • Eugenio Bringas
  • Özcan Köysüren
  • Dat V Quach
  • Morteza Mahmoudi
  • Elena Aznar
  • John D Roehling
  • M Dolores Marcos
  • Ramón Martínez-Máñez
  • Pieter Stroeve
چکیده

We report here the on-command cargo controlled delivery using an alternating magnetic field (AMF) from magnetic silica mesoporous supports capped with a lipid bilayer.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Triggered Release from Thermoresponsive Polymersomes with Superparamagnetic Membranes

Magnetic polymersomes were prepared by self-assembly of the amphiphilic block copolymer poly(isoprene-b-N-isopropylacrylamide) with monodisperse hydrophobic superparamagnetic iron oxide nanoparticles (SPION). The specifically designed thermoresponsive block copolymer allowed for efficient incorporation of the hydrophobic nanoparticles in the membrane core and encapsulation of the water soluble ...

متن کامل

Using hyaluronic acid-functionalized pH stimuli-responsive mesoporous silica nanoparticles for targeted delivery to CD44-overexpressing cancer cells

In this study, novel hyaluronic acid-pH stimuli-responsive lipid membrane mesoporous silica nanoparticles (HA-PL-MSNs) were designed and assembled, with the chemotherapeutic agent doxorubicin (DOX) as the model drug. HA-PL-MSNs exhibited a well-defined mesostructure covered by lipid bilayer and particle size of ~150 nm. The drug loading capacity was up to ~18.2%. DOX release could be effectivel...

متن کامل

Magnetic mesoporous silica nanoparticles for potential delivery of chemotherapeutic drugs and hyperthermia.

Magnetic mesoporous silica (MMS) nanoparticles with controllable magnetization have been synthesized by encapsulating Fe3O4 nanoparticles in a mesoporous silica matrix. The structure, magnetic heating capacity and drug delivery ability of MMS nanoparticles were evaluated. The results showed that MMS nanoparticles had an average particle size of 150 nm and showed low cytotoxicity and efficient c...

متن کامل

A molecular nanocap activated by superparamagnetic heating for externally stimulated cargo release.

A novel thermoresponsive snaptop for stimulated cargo release from superparamagnetic iron oxide core - mesoporous silica shell nanoparticles based on a [2 + 4] cycloreversion reaction (retro-Diels Alder reaction) is presented. The non-invasive external actuation through alternating magnetic fields makes this material a promising candidate for future applications in externally triggered drug del...

متن کامل

ULTRASOUND ASSISTED NON-SEEDED METHOD ON SURFACE MODIFICATION OF SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING PROBE by BASHIRU KAYODE SODIPO A thesis submitted in fulfilment of the requirements for the degree of Doctor of Philosophy

............................................................................................................... XVII CHAPTER 1: INTRODUCTION ................................................................................... 1 1.1 NANOTECHNOLOGY ................................................................................................ 1 1.2 SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES ........

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chemical communications

دوره 48 45  شماره 

صفحات  -

تاریخ انتشار 2012